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736 Purity (HPLC) >= 95% Solubility DMSO
Product Name DOTA-tris(t-Bu)ester-propargyl Synonyms CAS Number 911197-00-7 Related CAS Molecular Formula C31H55N5O7 Molecular Weight 609
Product Name tert-butyl 4-(piperazin-1-yl)butanoate Synonyms CAS Number n/a Related CAS Molecular Formula C12H24N2O2 Molecular Weight 228
85 SMILES Cl
Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 736 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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