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and Hoechst Janelia Fluor 646 (Hoechst-JF646)
Product Name Pomalidomide-C5-amine HCl Synonyms Pomalidomide-4'-C5-amine HCl CAS Number 2375194-03-7 Related CAS 2093386-39-9 (free base) Molecular Formula C18H23ClN4O4 Molecular Weight 394
S)-AHPC-CO-PEG4-C2-Br Synonyms CAS Number n/a Related CAS Molecular Formula C33H49BrN4O8S Molecular Weight 741
CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg and Hoechst Janelia Fluor 646SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to
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