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PEG linkers enhance water solubility and provide spatial separation to minimize steric hindrance during binding interactions
Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C93H121FN10O25 Molecular Weight 1798
066 Purity (HPLC) >= 95% Solubility DMSO
Product Name SHP099 Synonyms CAS Number 1801747-42-1 Related CAS Molecular Formula C16H19Cl2N5 Molecular Weight 352
DBCO-Dap(m-PEG4)-Val-Ala-PAB-PNP Thalidomide PEG linkers enhance water solubilitySOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,
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