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NRX-1532 ketone NCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

SKU 67022975179
4.9
USD190.00 USD217.00

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Description

NCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Compound AN2 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

Product Name Thalidomide-5'-O-C6-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C19H24ClN3O5 Molecular Weight 409

351 SMILES O=C(CCC#C)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NRX-1532 ketone NCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%NRX 1532 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 1532 Synonyms CAS Number n a Related CAS Molecular Formula C16H11F3N4O2 Molecular Weight 348. 285 SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=CC=NN2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid

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