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Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C70H91FN10O22 Molecular Weight 1443
Product Name BG-SulfoCy3 Synonyms SNAP-SulfoCy3 CAS Number Related CAS Molecular Formula C43H48N8O8S2 Molecular Weight 869
72 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
has enhanced potency in PIK3CA mutant models through a unique mechanism of action
DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE deuterium-labeled-amine Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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