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This dual reactivity forces the tagged proteins into close proximity
It has been used as a fluorescent substrate/probe to study the distribution and mechanism of action of multidrug resistance-associated protein 2 (Mrp2)
532 Purity (HPLC) >= 95% Solubility DMSO
Product Name CA-Alexa Fluor 488 Synonyms Alexa Fluor 488-Halo
DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg This dual reactivity forces theSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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