DOTA-tris(t-Bu)ester-PEG1-C2-propanamido-maleimide ketone Nature Chemical Biology

Nature Chemical Biology

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of 150

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DOTA-tris(t-Bu)ester-PEG1-C2-propanamido-maleimide ketone Nature Chemical BiologyDOTA bifucational chelator containing a thiol reactive maleimide group, a PEG linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA tris(t Bu)ester PEG1 C2 propanamido maleimide Synonyms CAS Number n a Related CAS Molecular