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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg HaloPROTAC3 achieves up to 90%

SKU 52923749006
4.6
USD495.00 USD530.00

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Ships within 48 hours · Estimated delivery Aug 8 - Aug 13

Description

HaloPROTAC3 achieves up to 90% degradation of GFP-HaloTag7 at a concentration of 625 nM

The water soluble 5(6)-TAMRA PEG3 alkyne has a long PEG3 spacer that separates the dye tetramethylrhodamine (commonly known as TMR or TAMRA) from the terminal acetylene group

CA-SS–Alexa488 fully labels recombinantly expressed Halo-tag proteins

Product Name Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C75H92FN11O23 Molecular Weight 1534

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg HaloPROTAC3 achieves up to 90%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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