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Signal Transduction and Targeted Therapy
Product Name Thalidomide-5'-O-PEG4-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C24H28N2O9 Molecular Weight 488
1038/s41586-019-1722-1
Isoindole-
PC-6 Size:100nmol Signal Transduction and Targeted TherapyPC 6 is a specially designed fluorescent probe for detecting SARM1 activity, built by conjugating a styryl donor group to a pyridine acceptor to form a donoracceptor system. It functions through SARM1s base exchange reaction, where PC 6 is converted into a positively charged product (PAD6) upon incorporation into NAD, leading to strong intramolecular charge transfer and a large fluorescence shift (from ~430 nm to ~520 nm). Among a series of related
